Animal-human embryo research is approved

Mark Henderson, Science Editor
Experiments to create Britain’s first embryos that combine human and animal material will begin within months after a government watchdog gave its approval yesterday to two research teams to carry out the controversial work.

Scientists at King’s College London, and the University of Newcastle will inject human DNA into empty eggs from cows to create embryos known as cytoplasmic hybrids, which are 99.9 per cent human in genetic terms.

The experiments are intended to provide insights into diseases such as Parkinson’s and spinal muscular atrophy by producing stem cells containing genetic defects that contribute to these conditions. These will be used as cell models for

investigating new approaches to treatment, and to improve the understanding of how embryonic stem cells develop. They will not be used in therapy, and it is illegal to implant them into the womb. The decision, taken by the by the Human Fertilisation and Embryology Authority (HFEA), to grant one-year licences to both teams ends more than a year of uncertainty for the researchers, who first applied for permission in the autumn of 2006.

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Last January the authority deferred its decision and began a consultation on the issue, which reported in September that the public was broadly supportive. In late November, it again delayed ruling because of concerns about procedures for obtaining consent from the donors of the human DNA to be used.

While the HFEA was deliberating, the Government proposed a ban on the creation of human-animal embryos, also known as “cybridsâ€