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  1. #1
    Senior Member Airbornesapper07's Avatar
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    Moderna launches clinical trial for HIV vaccine that uses mRNA technology The first p

    Moderna launches clinical trial for HIV vaccine that uses mRNA technology

    The first participants were given doses of the vaccine Thursday.

    ByMary Kekatos
    January 27, 2022, 3:08 PM
    • 5 min read



    On Location: March 25, 2022
    Catch up on the developing stories making headlines.

    Maddie Meyer/Getty Images, FILE

    Moderna announced Thursday that it's launched early-stage clinical trials of an HIV mRNA vaccine.
    The biotechnology company has teamed up with the nonprofit ​​International AIDS Vaccine Initiative to develop the shot, which uses the same technology as Moderna's successful COVID-19 vaccine.




    MORE: Moderna begins testing omicron-matched COVID shots in adults

    The first participants in the Phase I trial were given doses at George Washington University School of Medicine and Health Sciences in Washington, D.C., according to a company statement.
    "We are tremendously excited to be advancing this new direction in HIV vaccine design with Moderna's mRNA platform," Dr. Mark Feinberg, president and CEO of IAVI, said in a statement. "The search for an HIV vaccine has been long and challenging, and having new tools in terms of immunogens and platforms could be the key to making rapid progress toward an urgently needed, effective HIV vaccine."




    Maddie Meyer/Getty Images, FILE
    A view of Moderna headquarters in Cambridge, Mass., May 8, 2020.

    Nearly 38 million people worldwide -- including about 1.3 million in the U.S -- are living with HIV, or human immunodeficiency virus, which can lead to the potentially fatal disease AIDS.
    Being diagnosed with HIV was once considered a death sentence. During the height of the U.S. AIDS epidemic in the mid-1990s, more than 50,000 deaths occurred every year, according to the Centers for Disease Control and Prevention.

    Today, HIV is much more manageable with medications that can reduce viral loads to undetectable so the virus can't be transmitted, as well as pills that can be taken to prevent infecting those who are HIV-negative.
    But despite decades of research, no vaccine has ever been developed. Several candidates have entered clinical trials but failed in later stages.
    The new vaccine uses mRNA, or messenger RNA, which teaches the body's cells how to make proteins that trigger immune responses.

    Moderna
    @moderna_tx

    ANNOUNCEMENT : We are proud to announce that the first participant has been dosed in the Phase 1 study of mRNA-1644, our experimental
    #HIV#mRNA#vaccine candidate. Learn more about this exciting venture with @IAVI: https://investors.modernatx.com/news/news-details/2022/IAVI-and-Moderna-Launch-Trial-of-HIV-Vaccine-Antigens-Delivered-Through-mRNA-Technology/default.aspx…

    9:06 AM · Jan 27, 2022

    Researchers have developed not only a primary vaccine but also a booster to deliver HIV immunogens -- molecules that elicit an immune response -- via mRNA.
    The hope is this process can induce specific white blood cells, called B cells, which can then turn into what are known as broadly neutralizing antibodies that can neutralize the virus.
    According to the statement, Phase I of the trial will enroll 56 healthy, HIV-negative adult participants at GWU and three additional sites: Hope Clinic of Emory Vaccine Center in Atlanta; Fred Hutchinson Cancer Research Center in Seattle; and the University of Texas-Health Science Center at San Antonio.
    Of the volunteers, 48 will receive one or two doses of the mRNA vaccine, and 32 also will receive the booster. The remaining eight will receive just the booster.
    MORE: Biden administration speaks out on federal blood donation policy impacting gay men amid national blood shortage

    Researchers will then monitor for safety and efficacy of the new vaccine for up to six months after participants receive their final dose.
    Moderna did not immediately respond to ABC News' request for comment.
    ABC News' Sony Salzman contributed to this report.

    Moderna launches clinical trial for HIV vaccine that uses mRNA technology - ABC News (go.com)


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  2. #2
    Senior Member Airbornesapper07's Avatar
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    WOW... get V-A.I.D.S from Fauci's Vaxx and Moderna who is one of the companies that gave you V-A.I.D.S from Fauci's Vaxx is standing by with the medicine to ease your suffering before you die... but for a price

    Moderna launches clinical trial for HIV vaccine that uses mRNA technology
    Last edited by Airbornesapper07; 03-28-2022 at 12:43 AM.
    If you're gonna fight, fight like you're the third monkey on the ramp to Noah's Ark... and brother its starting to rain. Join our efforts to Secure America's Borders and End Illegal Immigration by Joining ALIPAC's E-Mail Alerts network (CLICK HERE)

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